BOTOX® has been used in the medical field for the past thirty years. Aesthetic use of BOTOX® began about ten years ago. The aesthetic application uses tiny amounts in comparison to when it is used to stop muscular spasms. Cosmetic BOTOX® is a prescription medicine that gets injected in small doses into facial muscles of the lower brow and the forehead in order to reduce the progress of deep wrinkles and enhance the look of frown lines, laugh lines, and fine lines.